Fucoidan Effect on Leukemia May Benefit Humans, Dogs and Cats

A new study published in the Journal of Cellular Physiology (Vol 231 Issue 3, pages 688–697, March 2016) has found that fucoidan, which is a component of brown seaweeds, suppresses certain leukemia cells.

Fucoidan inhibits leukemiaResearch Details

Researchers at Menzies Institute for Medical Research used human acute myeloid leukemia cells for this study. The cells were treated with fucoidan and analyzed. The study demonstrated the fucoidan effectively suppressed the proliferation of the leukemia cells, and induced apoptosis, which is the death of the cells through activation of natural killer cells. Addition of pan-caspase  (an essential part of cells that regulates cell death) inhibitor resulted in significant cell cycle arrest.

As part of the study, mice were given an oral dose of fucoidan and measured for tumor growth after being inoculated with tumor cells. The results demonstrated that oral doses of fucoidan significantly delayed tumor growth and increased the rate of splenic “natural killer cells”.

The results and implications for treatment of Leukemia in humans, dogs, cats and other species.

The combined results of the study, showing inhibition of leukemia cells and significant death of leukemia cells, led researchers to determine fucoidan should be investigated as an agent for treatment in acute myeloid leukemia.

This of course has an impact on leukemia that affects dogs, cats and other animals as well as humans, as proven by the studies effects on mice.

View the study: DOI: 10.1002/jcp.25119